Bioanalysis Laboratory

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The aim of the Bioanalysis Laboratory, established in 2010, is to do research on field of biometrology. The research is mainly on:

  • Development of primary reference methods in life sciences
  • Participation to international comparison studies
  • Production of Certificated Reference Materials (CRM)
  • Organization of national proficiency tests
  • Our laboratory has a full membership to BIPM and CCQM as well as JCTLM. Our goal is to provide a consensus in biological measurements in biological measurements nationally as well as internationally.

Research Subjects:

  • Studies based on Nucleic acid quantification

Studies are targeted on measurements of bio-macromolecules like DNA and RNA in high accuracy with low uncertainty values.

  • New methods are developed for quantification of genetically modified organisms (GMO) in agricultural products using reference DNA measurement methods.
  • Detection of changes in the mRNA levels, an indication for early diagnosis of many diseases.
  • Detection of changes in methylated DNA, used in early diagnosis of many cancers.
  • Production of CRM, required by laboratories measuring GMOs in agricultural products in Turkey, and organization of PTs.

 

  • Studies based on protein quantification

Studies are targeted on quantitative measurements of proreins and peptides, as well as enzyme activity measurements in high accuracy with low uncertainty values.

  • Meausurement of peptide and/ or protein levels quantatively with mass spectrometric and immonological methods
  • Develeopment of new methods for enzyme activity measurement.
  • Production of CRM, required by clinical laboratories in Turkey, and organization of PTs.

 

  • Studies based on quantification of cells.
  • Development of new reference measurement methods based on counting of blood cells in flow cytometry.

 

The research studies mentioned above are part of the project funding:

  • TÜBİTAK Projects
  • EMRP (European Metrology Research Programme) projects under EURAMET (European Association of National Metrology Institutes)
  • Participation of international comparison studies organized by BIPM CCQM

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